This article is based on a scientific study that analyzes the antibiofilm activity of essential oils from the Lamiaceae family against Candida albicans. The full study can be accessed through the link provided at the end of the article. In the following sections, we will explore the findings of this study and focus on two specific essential oils: thyme and oregano, due to the promising results they showed in this research. Additionally, we will expand on the benefits and properties of these essential oils.
Introduction
Essential oils have gained popularity not only for their pleasant aromas but also for their numerous therapeutic properties. Having essential oils in our home medicine cabinet can be very useful for treating a variety of common ailments naturally and effectively. Among their applications are their antimicrobial, anti-inflammatory, and antioxidant properties, making them valuable allies for ocular and general health. This article focuses on how thyme and oregano essential oils can be particularly effective in treating eye infections caused by Candida albicans.
Ocular Problems Caused by Candida Albicans
Save Your Eyes from Common Infections
Candida albicans can cause severe eye infections, such as:
- Endophthalmitis : Inflammation of the interior of the eye that can occur after surgeries or eye trauma, or through hematogenous dissemination in patients with candidemia.
- Fungal Keratitis : Infection of the cornea that can result from corneal injuries or the use of contaminated contact lenses.
Symptoms
Symptoms of eye infections caused by Candida albicans include:
1. Eye pain
2. Decreased visual acuity
3. Redness
4. Photophobia (sensitivity to light)
5. Blurred vision
6. Eye discharge
7. Corneal ulcer visible upon ophthalmologic examination
Importance of Treatment
It is crucial to treat these infections urgently to prevent severe complications, including blindness. Proper management includes the use of topical and systemic antifungals, and in severe cases, surgical intervention may be necessary.
Antibiofilm Activity of Essential Oils from the Lamiaceae Family against Candida Albicans
Introduction to the Study
Candida albicans is known for its ability to form biofilms, multicellular structures that give it resistance to conventional treatments. The study evaluated the antifungal and antibiofilm activity of five essential oils from the Lamiaceae family: Salvia officinalis , Thymus vulgaris , Rosmarinus officinalis , Origanum vulgare , and Hyssopus officinalis .
Materials and Methods
Antifungal Evaluation
The antifungal effect of essential oils (EOs) on planktonic cells of C. albicans was investigated, with concentrations ranging from 200 to 0.4 mg/mL, including 13 clinical isolates and a reference strain for biofilm formation.
Biofilm Evaluation
The ability of C. albicans to form biofilms was determined, classifying them into weak (69.2%) and moderate (30.8%) producers.
Results
Antifungal Activity
Thymus vulgaris (Thyme) and Origanum vulgare (Oregano) essential oils were the most effective against planktonic cells, with a minimum inhibitory concentration (MIC) of 0.4 mg/mL. In contrast, Salvia officinalis showed lower effectiveness with higher MIC values.
Antibiofilm Activity
Origanum vulgare and Thymus vulgaris demonstrated notable antibiofilm activity, inhibiting both the adhesion phase and biofilm formation at effective concentrations of 0.1-0.4 mg/mL.
Study Conclusions
Thymus vulgaris and Origanum vulgare essential oils have significant potential as antifungal and antibiofilm agents, making them promising alternatives for the treatment of resistant fungal infections.
Technical and Commercial Names of Essential Oils
To better understand the essential oils discussed, here are the technical names and their common and commercial names:
- Salvia officinalis : Common and commercial name - Sage Essential Oil
- Thymus vulgaris : Common and commercial name - Thyme Essential Oil
- Rosmarinus officinalis : Common and commercial name - Rosemary Essential Oil
- Origanum vulgare : Common and commercial name - Oregano Essential Oil
- Hyssopus officinalis : Common and commercial name - Hyssop Essential Oil
Properties and Benefits of Thyme Essential Oil ( Thymus vulgaris )
Key Benefits
Thyme is an aromatic plant with multiple health benefits for ocular health due to its antioxidant, anti-inflammatory, and antibacterial properties.
Antioxidants
Rich in flavonoids and polyphenols, thyme protects ocular cells from oxidative damage and prevents diseases such as macular degeneration.
Anti-inflammatory and Antibacterial
Thyme reduces ocular inflammation and prevents infections thanks to its anti-inflammatory and antibacterial properties, alleviating conditions such as conjunctivitis and dry eye syndrome.
Improves Blood Circulation
Thyme improves blood circulation, essential for maintaining healthy eyes and preventing complications related to high blood pressure and diabetes.
Practical Applications
- Thyme Infusion : Used for eye washes that reduce inflammation and irritation.
- Thyme Essential Oil : Applied topically (diluted) to reduce inflammation and protect against infections.
- Dietary Consumption : Incorporating thyme into the daily diet to take advantage of its antioxidant and anti-inflammatory benefits.
Precautions
It is essential to properly dilute thyme essential oil and avoid direct contact with the eyes. Consulting with a healthcare professional before using thyme to treat specific eye problems is highly recommended.
Properties and Benefits of Oregano Essential Oil ( Origanum vulgare )
Key Benefits
Oregano oil is known for its antifungal and antiseptic properties, being an effective remedy for various infections, including those caused by C. albicans.
Main Properties
- Carvacrol : Fights free radicals and protects against infections.
- Thymol : Antimicrobial and anti-inflammatory, strengthens the immune system.
- L-4 Terpineol and Vitamin E : Improves eye health, alleviating pain and inflammation and improving blood circulation.
Practical Applications
Oregano oil should be diluted before consumption or topical application to avoid irritation. Consulting a specialist about dosage and usage is crucial to avoid adverse effects.
Precautions
It is important to follow dilution recommendations and consult with a healthcare professional before using oregano oil for specific problems.
Conclusion
Thymus vulgaris (Thyme Essential Oil) and Origanum vulgare (Oregano Essential Oil) represent promising alternatives in the treatment of ocular infections caused by Candida albicans due to their antifungal and antibiofilm activity. Additionally, thyme and oregano oil offer multiple benefits for ocular health through their antioxidant, anti-inflammatory, and antibacterial properties. However, it is crucial to use them with caution and under the guidance of a healthcare professional to ensure their efficacy and safety.
Article written by Beatrice Pieper, General Coordinator of the International Institute of Visual Health
Reference Study:
Antibiofilm activity of essential oils from the Lamiaceae family against Candida albicans. (2024). [Full Study](https://www.aaem.pl/pdf-135892-65782?filename=Antibiofilm%20activity%20of.pdf).
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